Research a current venue for any major professional sport. Find the “guest code of conduct” on the venue’s web page. Put yourself in the shoes of the Event Manager. Why must a venue have a code of conduct? Are the rules of the establishment thorough and just or are they over the top? Is there anything else that needs to be added (hint: consider the surrounding areas of the stadium, current events, etc)? Where would be appropriate to display the “Code of Conduct” in the stadium/park (aside from the website)?The purpose of the exercise will gauge your understanding of event management and event planning and to continue to focus on writing clearly on concisely. Please use a minimum of 200 words.You may NOT use Citizens Bank Park (Phillies stadium). As an example, review Phillies Code of Conduct.You may utilize outside resources to supplement your assignment. However, all work must be cited. Please utilize APA formatting for your paper. Submissions should be a minimum of 300 words. To review the grading criteria, see the rubric below.
Wilmington Week 4 The Guest Code of Conduct in Yankee Stadium Research Paper
Sea Water Injection System
In order to improve the oil recovery in an oil field the injection of sea water is used to increase the pressure inside the reservoir and enhance the oil production. The graph given in Figure 1 is a typical seawater injection system, before the injection process, water must have a treatment to decrease the corrosion rate caused by seawater in pipe lines, surface and downhole injection equipments. The treatment is based in a mechanical de-aeration process and chemical scavenger injection to decrease the concentration of oxygen in seawater. Figure 1. Seawater Injection System In a normal operation of the seawater injection system the conditions of the process are 150,000 barrels per day, pipe diameter of 8 inches at 25 Â°C, however in terms of corrosion parameters the data is provided in table 1, this table shows that the mechanical deaeration process reduce the most quantity of Oxygen concentration in seawater. Table 1. Concentration of Oxygen in normal operation Concentration of O2 in different Units PPB mg/l mole/m3 Feed Seawater 7,000 7 0.22 After mechanical de-aeration process 100 0.1 0.003 After scavenger dosage 10 0.01 0.0003 With the data provided, the corrosion rate in normal operation condition is 0.0454mm/year (the calculation step by step including unit conversion are shown in the appendix) hence the corrosion rate is far less than the company acceptable value which is 0.1 mm/year, and it means that the system is working properly. It has been found that the mechanical de-aeration equipment requires repair, and it will be out of operation for between one and three months. Water system Injection without a mechanical de-aeration process: Calculating the limit current density with the following equation: Concentration of Oxygen only with the addition of Scavenger dosing = 6.910 ppm K is the mass transfer coefficient and it calculations and unit conversions are shown in the appendix. Calculating the Corrosion Rate: Assuming the main component of the pipe Iron therefore n= 2 M= 55.84 g/mol Density: 7.87 g/cm3 Now we can compare the corrosion rate of each case and determine the implications of operating the system without the mechanical de-aeration. Hence the corrosion rate will increase 502 times without the mechanical de-aeration. Based on this result it is obvious that the most important process for oxygen removal is the mechanical deareation. The company request the assessment in a technically and economically point of view three operational solutions during the repair of the mechanical de-aeration equipment. For the given acceptable corrosion rate less than 0.1 mm/year, a corrosion rate value of 0.09 mm/year was used to calculate the implications of the possible solutions. a. Decreasing the Flow Rate Assuming an acceptable corrosion Rate of 0.09 mm/year, From the equation above we can reach the Current density: With current density we can reach mass transfer coefficient k: Now we can reach the new Sh number: With Sh number we can obtain Re number: This value of Reynolds number means that we are in the transition regime between laminar flow and turbulent flow. Now we can reach the flow rate: From the technical point of view and based on the concepts of fluids mechanics, decreasing the flow volume to 260 barrels per day will generate a laminar flow (Re less than 3000) on the pipe, in other words it means that the velocity will not be in the required optimum range of 1.5 m/s to 2.5 m/s, according to Streeter. Doing the calculations the velocity will reach a very slow value of 0.014 m/s in the pipe, which is by far lower than the minimum value of 1 m/s. Therefore technically, the reduction of flow rate to reach an acceptable corrosion rate is not a possible solution. In addition, this kind of diminution of the flow rate (577 times lower than the original) would have impacts on the oil well. Specifically, it would not be able to maintain the pressure at the desired level and therefore would have a big impact on oil production leading to money loss. b. Increasing the amount of scavenger Assuming an acceptable corrosion Rate of 0.09 mm/year From the equation below we can reach the concentration of Oxygen that we need to contain in the water in order to have an acceptable corrosion rate Using Sodium sulfate as scavenger the following reaction will proceed: Hence form the stoichiometry of the reaction the relation between the compounds will be 2 moles of Scavenger and 1 mole of Oxygen. Therefore the amount of scavenger Sodium sulfate needed is: => In an injection flow rate of 150,000 bbl/day Based on scavenger’s calculations we need to provide the system with a high amount of scavenger to reduce the oxygen concentration that gives an acceptable corrosion rate, it is up to 1.3 ton per day, it is nearly 80 times more than amount of scavenger used in normal operation, which is about 17 kg per day. On the economically point of view, if the scavenger will substitute mechanical de-aeration for a month, the need of scavenger will be approximately 40 ton per month. By using the commercial price of scavenger 0.64 USD/kg (https://www.icis.com), it will cost around 832 USD/day and scaling it to a month it will cost nearly 24,960 USD/month. c. Corrosion Inhibitor Corrosion inhibitor compound will reduce the corrosion rate by preventing both anodic and cathodic reactions. Anodic inhibitor will be adsorbed onto metal surface to form protective film and prevent metal dissolution while cathodic inhibitor will minimize O2 reduction reaction by forming non-conducting film on metal surface. And in technical terms it could be the solution of the problem. However, from the calculations, we know that corrosion rate without the mechanical deareation is 22.5 mm/year and the aim is to decrease the corrosion rate below 0.1 mm/year. Based on the corrosion inhibitor risk category that is proposed by Hedges (2000), if the expected uninhibited corrosion rate is graeter than 6 mm/year inhibition is unlikely to provide integrity for the full field life. Therefore corrosion control of the system could not be efficient with a only corrosion inhibitor because of the high requirement of availability. Based on the results of the three possible options, on the economically point of view decreasing the injection flow rate will impact in the production of oil, and decreasing the main product (oil) of the industry it will have terrible effects in the oil company. Therefore in the corrosion engineering point of view the most accurately solution is to increase the amount of scavenger (Na2SO3) in order to reach a corrosion rate of 6 mm/year and then with the addition of corrosion inhibitors the corrosion rate can be reduce to an acceptable value of less than 0.1 mm/year. The dosage of O2 scavenger has to be interrupted for 8 hours per week for the injection of the biocide. During this time if there was not the corrosion inhibitor, the Corrosion rate would be 22.5 mm/yr. but if the Corrosion inhibitor inhibition rate is 98.5% (as from 6mm/yr to 0.09mm/yr), the corrosion rate would be: Therefore the Corrosion rate would be: The Corrosion rate is slightly above the required norm (0.002 mm/yr), but in the worst case scenario, 3 months with no deaerator, due to the fact the Corrosion rate with the mechanical deaerator is 0.0454 mm/yr which is 0.0546 mm/year less than the required standard. So, in a year perspective the slightly more amount of Corrosion will be not significant and the system will work properly. Also, the amount of Na2SO3 needed to reach a CR of 6 mm/year is 905 Kg/day and it will cost around 580 USD/day. Finally, in order to choose the ideal corrosion inhibitor laboratory tests must be performed in the same seawater that will be used. In situ tests would help to assure the quality of the results. Streeter, Victor L. “Handbook of fluid mechanics.” McGraw-Hill, ed 1 (1961). Hedges, B. (2000) “The Corrosion Inhibitor Availability Model“, NACE International, Paper 00034. Water system Injection with a mechanical de-aeration process and Oxygen scavenger addition: Considering the water system injection above and the following data we can reach a corrosion rate value in the next steps. Data provided: Pipe Diameter: = 8 inch, therefore the Area A = 50.26 in2 = 0.032429 m2 Volume Flow Rate: = 150000 bbl/d Initial Oxygen Concentration = 7 ppm Concentration of Oxygen After Mechanical De-aeretion = 100 ppb Concentration of Oxygen After Scavenger dosing = 10 ppb Kinematic Viscosity: 1.05 X 10-6 m2/s Schmidt number = 505 Calculation of Re number: Calculation of Sh Number: In turbulent Flow calculation of Diffusion coefficient: From Sh number we can reach the mass transfer coefficient k: Now calculating the limit current density with the following equation: Concentration of Oxygen after mechanical de-aeration and Scavenger dosing = 0.01 ppm Calculating the Corrosion Rate: Assuming the main component of the pipe Iron therefore: n= 2 MFe: 55.84 g/mol Ï: 7.87 g/cm3 For 8 hours per week, the O2 scavenger dosing is interrupted for biocide to be injected. So, there is an Availability of : => The Corrosion rate at a concentration of 0.1ppm of O2 is: Water system Injection without a mechanical de-aeration process: Calculating the limit current density with the following equation: Concentration of Oxygen only with the addition of Scavenger dosing = 6.910 ppm Calculating the Corrosion Rate: Assuming the main component of the pipe Iron therefore n= 2 M= 55.84 g/mol Density: 7.87 g/cm3 Now we can compare the corrosion rate of each case and determine the implications of operating the system without the mechanical de-aeration. Hence the corrosion rate will increase 502 times without the mechanical de-aeration. Evaluation of the following operational solutions: Decrease the flow rate of water: Assuming an acceptable corrosion Rate of 0.09 mm/year From the equation above we can reach the Current density: With current density we can reach mass transfer coefficient k Now we can reach the new Sh number: With Sh number we can obtain Re number: This value of Reynolds number means that we are in the transition regime between laminar flow and turbulent flow. Now we can reach the flow rate: Increasing the amount of scavenger: Assuming an acceptable corrosion Rate of 0.09 mm/year From the equation above we can reach the Current density: From the equation below we can reach the concentration of Oxygen that we need to contain in the water in order to have an acceptable corrosion rate Using Sodium sulfate as scavenger the following reaction will proceed: Hence form the stoichiometry of the reaction the relation between the compounds will be 2 moles of Scavenger and 1 mole of Oxygen. Therefore the amount of scavenger Sodium sulfate needed is: Hence we need: In an injection flow rate of 150000 barrels per day
Harcum College Enterprise Risk management Responses
assignment writing services Harcum College Enterprise Risk management Responses.
I’m working on a computer science Discussion and need support to help me study.
After reading both articles this week, and any other relevant research you locate, please discuss the following:
Please summarize, in your own words, a description of enterprise risk management. Why do you feel ERM is different from traditional risk management?
Please make your initial post and two response posts substantive. A substantive post will do at least two of the following:
Ask an interesting, thoughtful question pertaining to the topic
Answer a question (in detail) posted by another student or the instructor
Provide extensive additional information on the topic
Explain, define, or analyze the topic in detail
Share an applicable personal experience
Provide an outside source (for example, an article from the UC Library) that applies to the topic, along with additional information about the topic or the source (please cite properly in APA 7)
Make an argument concerning the topic.
At least one scholarly source should be used in the initial discussion thread. Be sure to use information from your readings and other sources from the UC Library. Use proper citations and references in your post.
Beasley, M. S. (2016). What is Enterprise Risk Management? Retrieved from https://erm.ncsu.edu/az/erm/i/chan/library/What_is_Enterprise_Risk_Management.pdf
Hopkin, P. (2010). Fundamentals of Risk Management?: Understanding, Evaluating, and Implementing Effective Risk Management. Kogan Page. – https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=nlebk&AN=330814&site=ehost-live&custid=s8501869
After the initial post will provide the two student post please provide the replies for that
Harcum College Enterprise Risk management Responses
Medicinal Chemistry Science Deals With Drug Discovery Engine Biology Essay
Medicinal Chemistry Science Deals With Drug Discovery Engine Biology Essay. Medicinal Chemistry is the science that deals with the drug discovery engine that provides the tools for the rest of the organization so they can determine the importance of particular biological target The main objective of medicinal chemistry is the design and discovery of new compounds that can be use ased as adugs. Medicines are substances used to treat diseases. Drugs are molecules used as medicines to diagnose, cure, mitigate, treat or prevent disease. This process involves a group of workers from various branches such as chemistry, biology, biochemistry, pharmacology, medicine and computing,etc. The discovery or design of a new drug not only requires a discovery or design process but also the synthesis of the drug, a method of administration, the development of tests and procedures to establish how it operates in the body and a safety assessment Since ancient times the peoples of the world have had a wide range of natural products that they use for medicinal purposes. These products, obtained from animal, vegetable and mineral sources, were sometimes very effective. However, many of the products were very toxic and it is interesting to note that the Greeks used the same word pharmakon for both poisons and medicinal products Although many natural products used in pharmaceuticals in their original chemical structures, successful efforts have been made to improve their pharmaceutic and therapeutic properties by structural modifications. Some of these modifications are relatively simple, like esterification. Another approach to improving therapeutic properties is to identify the portion responsible for its biological activity and synthesize new molecules that are based on it. The first rational development of synthetic drugs was carried out by Paul Ehrlich And Sacachiro Hata who produced arsphenamine in 1910 by combining synthesis with reliable biological screening and evaluation procedures. Heterocyclic chemistry is the chemistry branch dealing exclusively with synthesis, properties and application of heterocycles. Heterocyclic compound is an organic compound that contains a ring structure containing atom in addition to carbon, such as sulfur, oxygen or nitrogen as part of the ring. They may be either simple aromatic ring or non-aromatic rings. Hundreds of thousand of new oraganic compounds are prepared annually ad many of them entered in pharmacological screens to determine the whether they have usuful biological activity.The techniques of molecular graphics and computational chemistry have provided novel chemical structure that have led to new drug. Coumarin3 is a flavonoid discovered originally in plants. It was first discovered in 1820 which was obtained from Tonka bean (Dipteyix odorata fabaceae).Coumarins also known as benzopyrons family of compounds in which benzene ring joined to pyron ring.The derivatives of coumarin occure usually as the secondary metabolite. They present in Roots,seeds and leaves of many plant species. Coumarin is found in many plants such as lavender, woodruff, sweet clover and also strawberries, cherries and cinnamon. The dietary exposure to benzopyrone is quite significant as these compounds found in many vegetables, fruits ,nuts, seeds, coffee and wine .It is estimated that average western diet contains approximately 1gm/day of mixed Benzopyrans therefore it is not difficult to see why extensive research into their pharmacological and therapeutic properties underway over many years. The coumarin nucleus has the many diverse biological properties. The natural coumarin known to have hepatoprotective, anabolic activity. The substituted coumarins reported antimicrobial ,anticancer, analgesic, anti-inflammatory, antiviral, herbicidal. They have been used as anticonvulsant, HIV Protease inhibitor, antihistaminic, sedative and hypnotics. Also used as Fluorescent dyes, optical brighteners and as additive to food and cosmetics. Coumarin having typical odor like vanilla beans. It is used in the preparations of flavors and fragrances. Warfarin is one of the coumarin derivatives which used as anticoagulant in thrombolytic disorders .It also used in the major surgery is occaimpanied by state called hypercoagulability4. The development of anticoagulant drugs owed its start to an investigation of a disease of cattle charecerised by massive hemorrhages. When cattle eat sweet clover that has spoiled, the dicoumarol makes the blood thin, leading (in more severe case) to internal and/or external bleeding. It has been also used as rat poison. Coumarin derivative also used in the treatment of lymphedema5 Which includes loss of functional ability, Physical discomfort and recurrent episodes of cellulites and lymphangitis moreover because of loss of concentration between lymph vessels and vein. specially observed in obes women and women after age 60.Coumarin related drugs are reported useful in these condition. It is observed that these drugs are reduces the pain and discomfort due to lymphedeme. They have been also reported to reduce the episodes of cellucities and lymphangitis Acquired Immunodeficiency Syndrome(AIDS) is a immune system degenerative disease caused by Human Immuno Virus(HIV) results in life threatening infections and malignancies. Coumarin analogs has been found to potent anti HIV agents Coumarins, an old class of compounds, are naturally occurring benzopyrene derivatives. A lot of coumarins have been identified from natural sources, especially green plants. The pharmacological and biochemical properties and therapeutic applications of simple coumarins depend upon the pattern of substitution. Coumarins have attracted intense interest in recent years because of their diverse pharmacological properties. Among these properties, their cytotoxic33 effects were most extensively examined. In this review, their broad range of effects on the tumors as shown by various in vitro and in vivo experiments and clinical studies are discussed. Hence, these cytotoxic coumarins represent an exploitable source of new anticancer agents, which might also help addressing side-toxicity and resistance phenomena. These natural compounds have served as valuable leads for further design and synthesis of more active analogues. In this review, plant derived coumarins and their synthetic analogues were systematically evaluated based on their plant origin, structure activity relationship and anticancer efficacy Coumarins6 have been roughly categorised as follows: a) Simple coumarins, b) Furanocoumarins, c) Pyranocoumarins, d) Biscoumarins and Triscoumarins CHEMISTRY OF COUMARINS7 Commen name: – Tonka bean camphor, coumarinlactone. Chemical name: – 2H-1-Benzopyran-2-one,2-Oxo-1,2-benzopyran,Benzopyran-2-one 2H-Benzopyran-2-one. REACTIONS OF COUMARIN :43 A) REACTION WITH ELECTRIPHILIC REAGENT: 1) Addition to carbonyl oxygen Addition of proton to carbonyl oxygen produces the hydroxybenzopyrelium salt. O-Alkylation requires more powerful alkylating agent. B) C-Substitution. In strong acidic media C-substitution of coumarin has been observed in both Rings.Bromination and chloromethylation are two examples of C-substitution. Bromination-rection with bromine results in simple addition across heterocyclic ring gives 3-bromocoumarin. B) REACTION WITH NUCLEOPHILIC REAGENT A) Hydroxides – Coumarins quantitatively hydrolysed to give salt of corresponding cinnamic acid (yellow colored liquid).which is difficult to isolate since acidification brings immediate relactonisation. B) Reaction with Grignard Reagent Coumarins react with Grignard reagent and gives mixture of products resulting from ring opening of initial carbon adduct. C) REACTION WITH REDUCING REAGENT The hydride reagent can either react at carbonyl carbon or at conjugate system hence tends to produce the mixture. D) CYCLOADDITION In Diles-Alder Reaction coumarins serves as dienophiles under forcing conditions. SOME KNOWN DERIVATIVES OF COUMARIN8,9 SYNTHESIS OF COUMARIN42 Pechmann Condensation: Lewis acid mediated condensation of phenol with Î²-ketoesters to produce coumarins is called pechmann condensation Kostanecki-Robinson Reaction Conversion of o- hydroxyaryl ketones to chromones and coumarins with aliphatic acid anhydrides in the presence of sodium salt of corresponding acid. COUMARIN EMPERICAL FORMULA – C6H9O2 MOLECULAR WEIGHT – 146gms PHYSICAL FORM -White crystals, flakes or powder SOLUBILITY – chloroform, alcohol, ether slightly soluble in water. MELTING POINT – 69 °C BOILING POINT – 290 °C GENERAL USES – Fixative agent in perfumer Used as flavouring agent Used in tobacco manufacturer Used a flavouring agent, but it has been prohibited since 1965. PHARMACOLOGICAL OR THERAPEUTICS USES It is a novel Anti-coagulant such as Warfarin. Antiadrenergic ,CNS depressant. Anticancer, Antifungal, Antibacterial, lowering cholesterol level. Diuretic ,in cosmetics, respiratory stimulant. HIV-protease inhibitor . Relationship between Chemical Structure and Anticoagulant Activity40 While several interesting relationships between chemical structure, physical properties and anticoagulant activity have been pointed out, we are still unable to define the minimum structural characteristics that are required to confer anticoagulant powers on a molecule . Following the identification of dicoumarol as the agent responsible for the haemorrhagic sweet clover disease of cattle, numerous attempts were made to modify the structure of the dicoumarol molecule to produce anticoagulants of enhanced therapeutic value. The fact that ethyl biscoumacetate (with its low water solubility) is a potent anticoagulant, while its water-soluble parent (carboxylic acid) is inactive, suggested that anticoagulant activity might be related, to some extent at least, to the lipophilic properties of the molecule. In support of this claim they showed that simple aliphatic ethers of 2 : 2- bis-(4-hydroxycoumarinyl-3)-ethano were comparable in anticoagulant activity to dicoumarol. The work of Stahmann, WolffMedicinal Chemistry Science Deals With Drug Discovery Engine Biology Essay
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What are pentoses? To what organic group do pentoses belong? Are nucleotides formed of only one type of pentose?
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