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Therapeutic Cloning to Obtain Embryonic Stem popular mba argumentative essay help Environmental Issues assignment help

Therapeutic Cloning to Obtain Embryonic Stem Cells Is Immoral “The point is to cause each of us to think deeply about whether there is any essential difference between the reality of [World War II] Nazi experiments and ‘therapeutic cloning. ‘” In this two-part viewpoint, David A. Prentice and William Saunders discuss the science and the ethics of therapeutic cloning. In the first part, Prentice argues that creating clones for the purpose of embryonic stem cell research, called “therapeutic cloning,” is no different from reproductive cloning, which creates a living human child.

Also, he points out, therapeutic cloning is not therapeutic for the embryo. In the second part of the viewpoint, Saunders builds on Prentice’s argument and goes even further. He argues that therapeutic cloning is really no different than the horrific experiments performed by the Nazis during World War II. Saunders notes that supporters of embryonic stem cell research contend that the research is beneficial to humankind; however, Saunders argues, the Nazis used this same reasoning to Justify research on the mentally ill, the disabled, and the feeble-minded.

Prentice and Saunders are senior fellows at the Family Research Council, a onservative Christian think tank and lobbying organization. As you read, consider the following questions: 1. Why does Prentice claim that therapeutic cloning will lead to reproductive cloning? 2. What was the point of the Nuremberg Code, according to Saunders? 3. Why does Saunders say that therapeutic cloning violates the Nuremberg Code? Part I Cloning always starts with an embryo. The most common technique proposed for human cloning is called somatic cell nuclear transfer (SCNT).

This cloning is accomplished by transferring the nucleus from a human somatic (body) cell into an egg cell which has had its chromosomes removed or inactivated. SCNT produces a human embryo who is virtually genetically identical to an existing or previously existing human being. Proponents of human cloning hold out two hopes for its use: (1) the creation of children for infertile couples (so-called “reproductive cloning”), and (2) the development of medical miracles to cure diseases by harvesting embryonic stem cells from the cloned embryos of patients (euphemistically termed “therapeutic cloning”).

All Human Cloning Produces a Human Being All human cloning is reproductive. It creates”reproduces”a new, developing human intended to be virtually identical to the cloned subject. Both “reproductive cloning” and “therapeutic cloning” use exactly the same technique to create the clone, and the cloned embryos are indistinguishable. The process, as well as the product, is identical. The clone is created as a new, single-cell embryo and grown in the laboratory for a few days.

Then it is either implanted in the womb of a surrogate mother (“reproductive cloning”) or destroyed to harvest its embryonic stem cells for experiments (“therapeutic cloning”). It is the same embryo, used for different purposes. In fact, the cloned embryo at that stage of development cannot be egg and sperm. Trying to call a cloned embryo something other than an embryo is not accurate or scientific. Biologically and genetically speaking, what is created is a human being; its species is Homo sapiens. It is neither fish nor fowl, neither monkey nor cow”it is human….

Created in Order to Be Destroyed “Therapeutic cloning” is obviously not therapeutic for the embryo. The new human is specifically created in order to be destroyed as a source of tissue C, as Robert P. Lanza and colleagues report in a 2000 JAMA article]: “[Therapeutic cloning] requires the deliberate creation and disaggregation ofa human embryo. Most cloned embryos do not even survive one week, to the blastocyst stage, when they are destroyed in the process of harvesting their cells. Experiments with lab animals show that even these early embryos have abnormalities in genetic expression….

Beyond the abnormalities caused by the cloning procedure, embryonic stem cells from cloned embryos will still face problems for their use, including the tendency to form tumors, and significant difficulties in getting the cells to form the correct tissue and function normally…. Therapeutic Cloning Leads to Reproductive Cloning Because there is no difference in the nuclear transfer technique or the cloned embryo, allowing “therapeutic cloning” experimentation to proceed will inevitably lead to “reproductive cloning. ” The technique can be practiced and huge numbers of cloned embryos produced.

In fact, the lead scientist of the South Korean team that first cloned human embryos in February 2004 in a press conference on their experiments that the cloning technique developed in their laboratory “cannot be separated from reproductive cloning. ” His statement affirms what others have pointed out before: allowing therapeutic cloning simply prepares the way for eproductive cloning. Human cloning is unsafe and unnecessary. There are no valid or compelling grounds”scientific or medical”to proceed. A comprehensive ban on human cloning is the only sufficient answer. Part II As Dr.

Prentice has shown, cloning indisputably destroys innocent human life. This basic truth should lead the world to reject human cloning. However, in an effort to extricate human cloning from this ethical vise grip, its supporters attempt to draw a distinction between human life, which begins at conception, and human “personhood,” which begins only at their say-so. Unfortunately, the arbitrary denial f “personhood” to human beings has a long and cruel history. The Nuremberg Code, formulated in the years after World War II, is particularly instructive with regard to the current debate on human cloning.

For instance, when the principal author of the report on human cloning issued by the National Academy of Sciences testified before the President’s Council on Bioethics, he stated that “reproductive cloning” would violate the Nuremberg Code: “The Nuremberg Code, with which I am in full agreement, outlines those kinds of things you would not simply [do] for the sake of knowledge that involve human subjects. ” The Nuremberg Code The Nuremberg Code is a body of ethical norms enunciated by the Nuremberg Tribunal, which, after World War II, had the responsibility of Judging the actions of the Nazis and their allies.

The point of the code was to restate and apply the established ethical norms of the civilized world. Nazis Deemed Some Life Unworthy Nazi laws had defined Jews and other “undesirables” as non-persons. Eventually, camps and killed. However, before the killing in the camps began, the Nazis had engaged in an extensive campaign of euthanasia against the mentally and physically handicapped, which not only foreshadowed but also prepared the way for the xtermination camps.

In his book The Nazi Doctors, Robert Jay Lifton draws our attention to a book titled The Permission to Destroy Life Unworthy of Life, written during the campaign. Lifton writes: [It was] published in 1920 and written Jointly by two German professors: the Jurist Karl Binding and Alfred Hoche, professor of psychiatry at the University of Freiburg. Carefully argued in the numbered-paragraph form of the traditional philosophical treatise, the book included as “unworthy life” not only the incurably ill but large segments of the mentally ill, the feeble-minded, and retarded and deformed children….

T]he authors professionalized and medicalized the entire concept; destroying life unworthy of life was “purely a healing treatment” and a “healing” work. The Nazis were determined to “cleanse” the genetic pool to produce “better” Aryans. Nazi officials announced that “under the direction of specialists all therapeutic possibilities will be administered according to the latest scientific knowledge. ” The result of this therapeutic treatment of “inferior” lives was that “eventually a network of some thirty killing areas within existing institutions was set up throughout Germany and in Austria and Poland.

In their book, The Nazi Doctors and the Nuremberg Code, George Annas and Michael Grodin reveal that: At the same time that forced sterilization and abortion were instituted for individuals of “inferior” genetic stock, sterilization and abortion for healthy German women were declared illegal and punishable (in some cases by death) as a “crime against the German body. ” As one might imagine, Jews and others deemed racially suspect were exempted from these restrictions. On November 10, 1938, a Luneberg court legalized abortion for Jews.

A decree of June 23, 1943, allowed for abortions for Polish workers, ut only if they were not Judged “racially valuable. ” Later, the Nazis created the extermination camps for the Jews and other “inferior” races. In the camps, Nazi doctors engaged in cruel experiments on the Jews, Gypsies, Poles, and others. They exposed them to extreme cold to determine the temperature at which death would occur. They injected them with poisons to see how quickly certain lethal elements moved through the circulatory system.

They subjected twins to all manner of disabling and brutal experiments to determine how genetically identical persons reacted to different conditions. Some of the experiments were nonetheless designed to preserve life”not of the subject, but of, for example, German pilots who were forced to parachute into freezing ocean waters. Everyone agrees the Nuremberg Code prohibits “reproductive cloning. ” What relevance does it have for “therapeutic cloning? If human embryos are human beings, then “therapeutic cloning,” which creates an embryo only to destroy it in the process of exploiting its stem cells, violates a cardinal principle of the Nuremberg Code: There is to be no experimentation on a human subject when it is known that death or disabling injury will result. Regardless of the good that might be produced by such experiments, the experiments are of their very nature an immoral use of human beings…. Subverting the Meaning of Healing Recall how the Nazis subverted the meaning of healing.

Recall how they used the them. Recall that the Nazis eliminated those “unworthy of life” in order to improve the genetic stock of Germany. Recall how the Nazis undertook lethal experiments on concentration camp inmates in order, in some cases, to find ways to preserve the lives of others. The point is not to suggest that those who support “therapeutic cloning” are, in any sense, Nazis. Rather, the point is to cause each of us to think deeply about whether there is any essential difference between the reality of those Nazi experiments and “therapeutic cloning. As we have shown, each case involves a living human being, and that human being is killed in the aim of a perceived “higher” good. Cloning proponents try to distinguish between the two cases by saying that the cloned human being has no “potential. ” But in each case, it is the actions of other human beings that rob the first of “potential” (in the first case, the actions of Nazi executioners; in the second, the laboratory technicians). In either case, the human ubject is full of potential simply by being a living human being. Of course, almost miraculously, many of the inmates of the camps did survive when the allies rescued them.

Equally miraculously, frozen embryos have been implanted in a woman’s womb and brought to live (and healthy) birth. As we have shown, every embryo is not merely “potentially” a life, but [is an] actual life, a human being from the first moment of existence. Furthermore, any living human embryo has the inherent “potential” to develop into a healthy baby. It is disingenuous for supporters of cloning to claim the cloned human embryo is only “potential life” because they plan o mandate by law that it be destroyed before it can come to birth.

Regardless of its location, the human embryo, by its nature, is full of potential, unless the actions of adult human beings deprive it of the opportunity to realize that potential. Guard Against Inhuman Acts [Russian author] Alexander Solzhenitsyn, a man who chronicled and suffered under another ideology that denied the dignity of each and every human being, observed, “Gradually it was disclosed to me that the line separating good and evil passes not through states, nor between classes, nor between political parties either, but right hough every human heart, and through all human hearts. This line shifts.

Inside us, it oscillates. ” Solzhenitsyn did not regard the perpetrators of brutal crimes in his own country as inhuman monsters. Rather, he saw the essential truth”they were human beings, engaged in immoral acts. They engaged in those acts by dehumanizing the persons on whom their brutality was inflicted, and they did so in the name of (perhaps in the passionate belief in) a greater good. But Solzhenitsyn reminds us that, unless we are willing to admit that, for the best as well as for the orst of motives, we are also capable of inhuman acts, we will have no guard against committing them.

No one is safe from brutality so long as we think that it is only inhuman others who are capable of inhuman acts. Rather, we will be secure when we are willing to look honestly at the objective reality of our acts, while realizing that we, too, are capable of acts that violate the inherent dignity of another, and refuse to engage in such acts despite the good we believe would result from doing otherwise. In the debate over the cloning and destruction of embryonic human beings, this essential truth must be our guide. Books Brian Alexander Rapture: How Biotech Became the New Religion.

DRUG ABUSE IN DAYTON- OHIO 3 Running Head: DRUG ABUSE IN DAYTON-

DRUG ABUSE IN DAYTON- OHIO 3

Running Head: DRUG ABUSE IN DAYTON- OHIO 1

Drug Abuse in Dayton- Ohio

Name

Institutional Affiliation

Substance Abuse – Dayton – Ohio

The objectives of the survey are to help in reducing the rates of drug abuse and unintentional drug prescription overdose deaths in Dayton-Ohio. According to the current data, many people die from drug overdoses each and every day. The County Sheriff’s deputies respond to multiple of drug overdose calls and are equipped with either naloxone or Narcan, which is a nasal spray which counteracts the drug overdose effects. The survey aims at making a progress in the fight against the heroin epidemic which has become deadly and largely responsible for the recorded number of deaths related to drug overdoses in the state.

The survey will seek to stabilize the amounts of deaths resulting from drug abuse and reducing the number of fatal overdoses. In addition to that, it will identify the services being offered; look in to the existing gaps in services while exploring potentially new and expanded ways for combating the drug abuse and overdose menace (Ekeh, Parikh, Walusimbi, Woods, Hawk & McCarthy, 2014).

As part of the collaborative approach, over 100 community leaders from private and public organizations throughout Ohio are members of the survey team which will help guide the project. All the aspects of minimizing deaths as a result of drug abuse and overdoses will be included in the effort, with every specific team working on treatment, prevention, law enforcement, opioid prescription guidelines, the court system, education and outreach.

In providing an overview, the specific objectives of the survey will include;

Patterns of multiple drug usage both concurrent and non-concurrent.

Beliefs over the harmfulness of different types of drugs at various levels of use.

Extents of direct exposure to different forms of drug use.

Perceived availability of the various illicit drugs.

Describing current treatment practices.

Assessing the impact of the intervention.

Studying the causes and consequences of drug abuse and overdoses.

Traditionally, illicit drug usage mostly is associated with dense populated towns. But, a mounting evidence proofs that this is has been a significant issue in rural areas as well. Young individuals comprising both men and women in the age bracket between 18 – 65 years being the most affected. This population abuse not only tobacco, alcohol, and marijuana but also drugs like amphetamines and cocaine. Heroin injection including the plethora of issues which are associated with it now threatens public health the Ohio region (Cameron, Delroy & et al, 2013).

This regional survey will be based upon the qualitative data which will be collected through the focus group interviews. The participants will include the recovering and active drug users recruited from alcohol and other various drug treatment programs sin Dayton – Ohio region. The data triangulation will be attained through comparing the participant data and the qualitative data which has already been collected from the regional professionals, who are the law enforcers and the treatment providers, through the focus group interview and the data surveyed from the authorities. All the secondary data are summaries of the cases which have been processed in the previous one year. In addition to these data sources, the Ohio media outlets will provide the most recent data regarding the drug abuse and overdose issue.

In an effort to understand the current drug epidemic in Dayton Ohio, the survey will summarize the drug related data collected in various different related organizations in to a one formal data report. The survey involves the related criminal justice data, the drug overdose responses by City of Dayton first responders, emergency and in-patient departments accidental overdose records, and the unintentional drug overdose death reports.

The survey conducted in the region can be used to inform the general public, the leadership as well as the organizations within the County as to the severity of the drug abuse and overdose menace. In addition, the survey report will be available to provide all the information required for the new program development, grant applications pertaining to the epidemic or informing policy decisions.

Qualitative interviewing technique will be used, ranging from informal interviews to semi structured interviews and life histories. Reason for applying interviewing technique is that, in an open-ended interview format, conversations are is allowed and can flow freely in reference to the topic. In contrast, a more structured interview a predesigned sets of discussion topics can be offered for one’s response. Interviewing technique generally, serves as means to determine how participants engage or talk about or perceive different aspects in their personal lives or how they categorize things. After the preliminary analysis, the information can be applied in creation of a more focused set of questions pertaining a certain research topic or problem.

Interviewing participants will play an important role of getting familiarity with how individuals perceive and express various dimensions regarding how they live. In particular cases, focus groups or group discussions comprising of four to six or more respondents, will be used in individual open-ended interviewing. Both techniques to be applied in the interviewing sessions will allow for the general discussion of the research questions. The focus groups will aim at exploring the research topics, refining interventions, obtaining feedback on the design, evaluating the quantitative survey instruments, guiding the refinement of more structured interviews and obtaining feedback on the preliminary analyses.

At least eight Ohioans die each day from accidental drug overdose and abuse. Communities and schools are in the frontlines of the crisis, and their efforts of educating the young generation over the dangers of drug abuse will help in building a better future. The survey includes various recommendations which will help in building a stronger drug-free generation;

By reducing the risk factors and the protective factors, the children will resiliency while making life decisions which are positive.

Screening for mental health issues and substance abuse require to be followed by the effective treatment and interventions.

A comprehensive, community-wide drug abuse prevention program should involve schools, caregivers, and parents, law enforcements, before and after school efforts, community coalitions and others to be effective (Carlson, Lane & Daniulaityte, 2014).

Questionnaire

Have you at anytime ever used drugs other than those required for the medication purpose________________?

Have you ever abused subscription drugs ________________?

Can you get6 through a week without using any type of drugs ________________?

Have you ever abused more than one drug at a time________________?

Are you always able to stop using drugs the time you want to________________?

Have you ever had flashbacks or blackouts as a result of using drugs________________?

Do you ever feel guilty or bad about your drug use________________?

Does your spouse or parents ever complain about your involvement in using drugs________________?

Have you ever lost a friend as a result of drug abuse or overdose________________?

Have you ever been in trouble at work as a result of drug use________________?

Have you ever neglected your family because of use of drugs________________?

Have you previously lost a job as a result of drug use________________?

Have you ever gotten into a fight when under drug influence________________?

Have ever engaged into illegal activities in order to obtain drugs________________?

Have you ever gone to anyone for help as a result of drug problems________________?

Have you been in any treatment program specifically related to drug usage________________?

Have you ever experienced any withdrawal symptoms or felt sick as a result of abusing drugs________________?

Have you had any medical issues as a result of your drug usage (e.g. hepatitis, loss of memory, convulsion, bleeding, etc) ________________?

Have you been arrested for possession of illegal drugs________________?

References

Cameron, Delroy, et al. “PREDOSE: a semantic web platform for drug abuse epidemiology using social media.” Journal of biomedical informatics 46.6 (2013): 985-997.

Carlson, R. G., Lane, D. T., Li, L., & Daniulaityte, R. (2014). Montgomery County Poisoning Death Review: 2010-2013.

Ekeh, A. P., Parikh, P. P., Walusimbi, M., Woods, R. J., Hawk, A., & McCarthy, M. C. (2014). The prevalence of positive drug and alcohol screens in elderly trauma patients. Substance abuse, 35(1), 51-55.